Research shows psilocybin increases inhibitory brain cell activity, reducing reward-seeking drive and offering a potential mechanism for treating substance use disorders. The findings suggest psychedelics may induce lasting changes in brain circuits relevant to addiction treatment.
PsyPost · Friday, 3 July 2026
A single dose of psilocybin reduces the drive to seek out rewards by increasing the activity of inhibitory brain cells. These findings help explain how psychedelics might induce long-lasting changes in brain circuits to treat substance use disorders.
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